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In T2DM model mice, which were induced by a high-fat diet combined with streptozotocin injection, miR-144-3p was up-regulated under hyperglycemic conditions, where it promoted -cell ferroptosis and impaired insulin secretion by directly targeting ubiquitin-specific peptidase 22 (USP22) and destabilizing the USP22/SIRT1 axis

Always use a new sterile needle for each injection

International Journal of Molecular Sciences , 19(7), 2102

A multicenter, randomized, evaluator-blinded, placebo-controlled clinical study evaluated the effectiveness of the glycyl-L-histidyl-L-lysine copper complex (lamin Gel) in treating diabetic neuropathic ulcers